DBI

qLabs PT/APTT Monitoring System Monitoring the Effectiveness of Blood Thinning Medication

A PT/INR test helps ensure the effectiveness of the anticoagulant drug warfarin (Coumadin®) and that prothrombin time and internationally normalized ratio is appropriately prolonged.  PT-INR tests measure the blood’s ability to clot. Blood normally clots to slow down it’s flow in response to the damage of blood vessels, in order to prevent excessive bleeding. A clot formed inappropriately in the areas of heart, lung and brain, however, can hinder normal blood flow and may result in life-threatening events such as stroke and heart attack. For patients who lose their ability to properly reabsorb clots and patients who have low tolerance to clots, anticoagulation medicine (blood thinner) is prescribed. Because these medications may have narrow therapeutic windows and be sensitive to diet and lifestyle, it may be necessary for patients to adjust their dosage regularly. In order to make good decisions regarding the need for such an adjustment, it is important for the patient to know the clotting status of their blood. PT or INR value from the PT-INR tests helps patients or healthcare professionals make these decisions. A quick and accurate measurement of PT or INR value is critical for the safety and effectiveness of the anticoagulation therapy. The clotting capacity of the blood is reported as a Prothrombin Time (PT) or an International Normalized Ratio (INR) value. qLabs® PT-INR Test Strips While PT times may vary depending on the test method used, INR values should be the same regardless of the method used. International Normalized Ratio (INR) is recommended by WHO to remove dependence on reagent and test method. The qLabs® ElectroMeter calculates the PT value based on an analysis of the test data, and then converts this to the correct INR value.

The qLabs PT/INR test is an easy-to-use finger-stick blood test, designed for professional or home use, that provides highly accurate results within 2 minutes. The dry reagent strips can be stored at room temperature for immediate use for up to 18 months, with no equilibration required.

The APTT test is used primarily to investigate unexplained clotting or bleeding. The qLabs APTT test is an easy-to-use finger-stick blood test, designed for professional use, that provides highly accurate results within 7 minutes. The dry reagent strips can be stored at room temperature for immediate use for up to 18 months, with no equilibration required. The APTT is a general coagulation test used for screening and measuring the functionality of the intrinsic coagulation pathway, which involves the coagulation factor XII, XI, IX, VIII, X, V, II and fibrinogen. It is also used to monitor the effectiveness of heparin therapy. The APTT is a modification of the Partial Thromboplastin Time (PTT); it can provide a more precise and sensitive assay. qLabs® APTT Test Strips The qLabs® APTT test strip measures the blood’s ability to clot which determines the Activated Partial Thromboplastin Time (APTT) on whole blood.

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FIBRITIMER ZETA-2

Upcoming Products: Zeta-2

At Dfine Bioinnovations, our R&D team is tirelessly pushing the boundaries of innovation to support diagnostics with cutting-edge, yet cost-effective solutions. Building on the success of Zeta-1, we are gearing up to launch Zeta-2, a two-channel semi-automatic coagulation analyzer designed to enhance efficiency and throughput for small to mid-size labs. Beyond this, we are exploring advanced automation and Point-of-Care Testing (POCT) solutions to offer a comprehensive range of diagnostic tools. These upcoming products underscore our commitment to revolutionizing healthcare with indigenous, affordable, and efficient innovations. Stay tuned for the next wave of transformative diagnostic technologies!

Coagulation Consumables

Manufacturing High
Quality Consumables

Instrument performance is directly tied to the quality of consumables, especially in critical diagnostic tests like coagulation. To ensure precision and reliability, Dfine Bioinnovations manufactures high-quality consumables such as buffer bottles, cuvettes, and stainless steel balls. These consumables not only support our flagship Zeta-1 coagulation analyzer but are also other devices like  XL-1000, MC-1, and KC Series, ensuring consistent performance across platforms. By offering durable, efficient, and precision-engineered consumables, we are setting new standards in diagnostic accuracy and reliability, meeting the needs of labs globally.

Product & Innovations Slide Image 3

Rigorous Product
Validation

FibriTimer Zeta-1 has undergone rigorous internal and external validation to ensure accuracy, reliability, and precision in its performance. Tested across leading labs and hospitals, it has demonstrated exceptional correlation and reproducibility for critical tests like PT/APTT. With its validation results published in the International Journal of Health Technology and Innovation (August 2024 issue), Zeta-1 stands as a trusted solution, empowering labs with dependable diagnostics and boosting confidence in patient care.

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Dual Technology

Dual Technology enhances lab efficiency by offering flexibility in result verification, especially for difficult samples. It boosts reporting confidence, expands test options on a single platform, and empowers small to mid-size labs by eliminating the need for multiple instruments for different tests and avoiding outsourcing. This leads to cost reduction and faster, more efficient reporting for timely patient treatment. Company has received Indian Patent(Patent no: 529922) for this technology.